Linear growth modeling of AAAs in individual patients suggests smaller AAAs (<4.25 cm) can be followed up with a CT scan in at least 2 years with little chance of exceeding interventional thresholds.Ĭ Identifier: NCT01756833. Most small AAAs showed linear growth large intrapatient variations in interval growth rates were infrequently observed over 2 years. Twenty-six percent of patients with a maximum transverse diameter of at least 4.25 cm exceeded sex-specific repair thresholds at 2 years (n = 12 of 83 men with diameter ranging from 4.25 to <4.75 cm 95% CI, 0.091-0.264 n = 21 of 44 men with diameter ranging from 4.75-5.0 cm 95% CI, 0.362-0.669 n = 3 of 10 women with diameter ≥4.25 cm 95% CI, 0.093-0.726). That’s all Except for py, the code is exactly what you would write to using the NI-VISA backend for PyVISA. No patients with a maximum transverse diameter less than 4.25 cm exceeded sex-specific repair thresholds at 2 years (men, 0 of 92 95% CI, 0.00-0.055 women, 0 of 25 95% CI, 0.00-0.247). Most AAAs displayed linear growth (70%) large variations in interval growth rates occurred infrequently (3% staccato growth and 4% exponential growth) and some patients' growth patterns were not clearly classifiable (23% indeterminate). Baseline AAA diameter accounted for 5.4% of variance of growth rate (P <. Ten percent of AAAs displayed minimal to no growth (0.25 cm/y). Yearly growth rates of AAA diameters were a median of 0.17 cm/y (interquartile range, 0.16) and a mean (SD), 0.19 (0.14) cm/y. Secondary analyses included characterizing AAA growth patterns, assessing likelihood of AAA diameter to exceed sex-specific intervention thresholds over 2 years.Ī total of 254 patients, 35 women with baseline AAA diameter 3.5 to 4.5 cm and 219 men with baseline diameter 3.5 to 5.0 cm, were included. The primary study outcome was AAA annual growth rate. Patients received serial CT scan measurements, analyzed for maximum transverse diameter, at 6-month intervals. Participants included 254 patients with baseline AAA diameter between 3.5 and 5.0 cm. The trial was a multicenter, observational secondary analysis, not related to treatment hypotheses of data collected in the N-TA3CT.
To assess the growth patterns and rates of AAAs as documented on serial computed tomography (CT) scans.Ĭohort study and secondary analysis of the Non-Invasive Treatment of Abdominal Aortic Aneurysm Clinical Trial (N-TA3CT), a randomized, double-blind placebo-controlled clinical trial conducted from 2013 to 2018, with CT imaging every 6 months for 2 years.
Their growth rates and patterns, which drive clinical surveillance, are widely disputed.
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